![]() ![]() ![]() Receipt of moderate oxycodone doses in these patients may significantly decrease pulmonary ventilation. Acetaminophen oxycodone use is contraindicated in patients with significant respiratory depression, and in patients with acute or severe asthma (e.g., status asthmaticus) or hypercarbia in unmonitored care settings or in the absence of resuscitative equipment. Additionally, avoid coadministration with other CNS depressants unless no other alternatives are available, as this significantly increases the risk for respiratory depression, low blood pressure, and death. Accidental exposure, asthma, chronic obstructive pulmonary disease (COPD), coadministration with other CNS depressants, cor pulmonale, hypoxemia, obesity, pulmonary disease, respiratory depression, respiratory insufficiency, scoliosis, sleep apnea, status asthmaticusĪs with other opiate agonists, products containing oxycodone should be avoided in patients with severe pulmonary disease. ![]()
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